Final injury report: Both the Bills and the Dolphins will be without important defensive players.

The Buffalo Bills and Miami Dolphins will play their opening game of the season on Sunday without important defensive players.

Before today's final practice, Bills head coach Sean McDermott notified the media that safety Jordan Poyer would miss Week Four's game at Highmark Stadium. Poyer has been nursing a knee issue from last week. See what we know here.

The remainder of the Bills are ready to play. All players except Poyer and Tre'Davious White (who had a vet rest day) participated in today's practice despite injuries throughout the week.

Dolphins linebacker Jaelan Phillips will miss the game. The third-year pro hasn't practiced since Sunday's oblique injury.

If Miami doesn't play Williams and Armstead, Tua Tagovailoa may struggle to dodge Buffalo's pass rush. The Dolphins may struggle without Ahmed, but rookie running back De'Von Achane delivered last week with 203 yards

 and two touchdowns on the ground and 30 yards and two more via the air. Raheem Mostert and Achane will keep the Buffalo run-defense busy.

Jaylen Waddle will run routes this week for the AFC East leaders. Waddle missed last week after failing concussion protocol after a Week 2 head blow. 

The Dolphins scored 70 points without their WR2, but quarterback Tua Tagovailoa will welcome Waddle back, especially since River Cracraft's shoulder injury could keep him out for more than this week. .

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